Researchers identify 135 new melanin genes responsible for pigmentation shorts pigmentation

Researchers have discovered 135 new genes linked to pigmentation by using CRISPR-Cas9 to modify melanocytes. This study identifies genes responsible for melanin production, impacting human skin color. Among the findings, KLF6 and COMMD3 genes were revealed, influencing melanin synthesis and acidity regulation in melanosomes. Understanding these genes could aid in preventing skin cancer and treating pigmentation disorders. The research's techniques could also target melanin-producing genes in fungi and bacteria for disease control. The study was supported by various grants and funding sources.

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